The Human Upgrade with Dave Asprey

Is AI About to Replace Your Doctor? Or Save Your Life? The tools that are reshaping healthcare will redefine medicine—and your life—in ways you’ve never imagined. Will artificial intelligence and regenerative therapies like stem cells and exosomes make doctors obsolete? Or will they finally unlock the secrets to living to 180? In this episode, Dave sits down with Dr. Pradeep Albert, a leader in regenerative medicine and AI-driven imaging, to explore the intersection of technology, longevity, and healing. Dr. Albert shares groundbreaking insights on how AI is revolutionizing medical diagnostics, replacing outdated systems, and empowering patients to take control of THEIR OWN health. He also dives deep into regenerative therapies—how PRP, exosomes, and stem cells are changing the game for injuries, inflammation, and aging. Can AI improve patient-doctor relationships? Are doctors becoming coaches instead of gatekeepers? And most importantly, how can you leverage these tools to outlive your peers and enhance every aspect of your health? What You’ll Learn: • Why 50% of people won’t make it past 76—and how to beat the odds • How AI is already better than doctors at diagnosing certain conditions • The truth about PRP, exosomes, and stem cells—and when to use each • The three rules of longevity every person needs to know • How your mindset and epigenetics can help you live longer and healthier Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Dr. Pradeep Albert’s Book: Exosomes, PRP, and Stem Cells…Medicine – https://www.amazon.com/Exosomes-Stem-Cells-Musculoskeletal-Medicine/dp/B0C2S59S8K Dr. Pradeep Albert’s Book: Lifespan Decoded –https://lifespandecoded.com/ Dr Pradeep Albert’s Website – https://drpradeepalbert.com/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. OneSkin | Go to https://oneskin.co/ and use code ASPREY15 for 15% off your purchase. Timestamps: • 00:00 – Introduction to AI in Medicine • 00:36 – The Role of AI in Longevity • 00:51 – Meet Dr. Pradeep Alpert • 01:11 – AI’s Impact on Healthcare • 02:07 – Changing Role of Doctors • 05:01 – AI in Medical Imaging • 06:37 – Orthopedics and AI • 09:19 – Longevity and Epigenetics • 14:16 – The Importance of Mindset • 29:08 – Trust in the Medical System • 43:18 – DIY Health and Longevity • 44:21 – The Future of Insurance and Medical Costs • 45:45 – Advancements in Imaging Technology • 47:26 – The Art of Physical Examination • 50:21 – Regenerative Medicine: PRP, Exosomes, and Stem Cells • 01:00:23 – Challenges in the US Medical System • 01:07:54 – The Role of AI in Medicine • 01:18:14 – Final Thoughts and Book Promotion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people don’t think about their liver until it’s too late. In this episode, Dave sits down with Siggi Clavien, founder of de-liver-ance® & The Liver Clinic, to uncover the hidden superpowers of the body’s most underrated organ: the liver. This is a deep dive into why your liver is the ultimate game-changer for your energy, brain power, and longevity. Siggi reveals groundbreaking insights on reversing fatty liver disease, boosting detoxification, and harnessing the liver’s regenerative capabilities. From fighting brain fog to protecting against toxins, this episode will have you rethinking everything about how you treat your body. And yes, your liver could be the key to living a healthier, happier life. Siggi also shares the science and innovation behind de-liver-ance®, his groundbreaking herbal product designed to deliver the most powerful results in a safe, natural way. Backed by millions of dollars and years of research, de-liver-ance® is setting a new standard in liver health. Use code: DAVE at https://us.loveyourliver.com/discount/DAVE to get a discount! Dave and Siggi also explore cutting-edge strategies to supercharge your liver health using natural herbs, breakthrough science, and biohacking tools. What You’ll Learn: • Why your liver holds the key to longevity, energy, and mental clarity • How to reverse fatty liver disease—even if you’ve been told it’s irreversible • The truth about common liver-destroying habits you need to ditch now • Groundbreaking ways to protect and regenerate your liver for optimal health • The science behind de-liver-ance® and how it’s changing liver health forever • Simple, actionable strategies to boost detoxification and supercharge your body Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 de-liver-ance® – https://us.loveyourliver.com/discount/DAVE (Use code DAVE at checkout for a discount!) The Liver Clinic – https://theliverclinic.com Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Timestamps: • 00:00 Intro • 00:00 Introduction and Liver Basics • 01:46 Guest Introduction and Liver Health Insights • 02:16 Understanding Liver Scans and Lab Panels • 05:13 Fatty Liver Disease: Causes and Consequences • 07:07 Diet and Liver Health • 09:47 Supplements and Liver Function • 11:53 Advanced Liver Health Strategies • 14:05 Biohacking and Liver Health • 17:41 Deliverance Supplement and Its Benefits • 23:12 Liver Health and Longevity • 31:12 Biohacking: The Path to Consciousness and Longevity • 32:29 The Liver: The Body’s Regenerative Powerhouse • 34:48 Gut Microbiome and Liver Health Connection • 35:59 Lipopolysaccharides: The Hidden Toxins • 40:44 Coffee: A Surprising Ally for Liver Health • 43:16 Mold Toxins: The Silent Liver Destroyers • 48:43 Hormone Health and the Liver • 52:19 Type 2 Diabetes, Menopause, and Liver Health • 52:43 The Impact of Lifestyle on Liver Health • 54:57 The Importance of Bile and Gallbladder Health • 58:06 Genetics, Toxins, and Liver Resilience • 01:06:25 Conclusion: Investing in Liver Health for a Better Life See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Will the next nuclear bomb be AI Superintelligence? The intelligence we’re building will reshape the world in ways we never imagined—for better or worse? But more importantly, what side will humanity take? In this episode, Mo Gawdat, bestselling author of Scary Smart and former Chief Business Officer of Google X, joins Dave to tackle the profound challenges and opportunities artificial intelligence presents. This isn’t about dystopian robots or tech hype—it’s about redefining what it means to be human in the age of machines. There’s hope, don’t worry! Mo dives into the reality of how AI is already shaping our behavior, our ethics, and even our potential for happiness. He reveals the critical need for aligning intelligence—human or artificial—with values that promote global abundance and collaboration. Dave and Mo mix data, philosophy, and bold visions, to show why our future depends on shifting from competition to cooperation. But most importantly, why all of this is going to make you a better YOU. What You’ll Learn: • The real reason AI is reshaping human behavior—and how to take back control • Why intelligence without ethics could lead to catastrophe • How abundance thinking can unlock limitless possibilities for humanity • The crucial mindset shifts leaders need to adopt before it’s too late • Practical insights for ensuring AI supports human flourishing, not destruction Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Mo Gawdat’s Book: Scary Smart – https://a.co/d/6DukqyW Mo Gawdat’s Book: Unstressable – https://a.co/d/hrbpY9O Follow Mo Gawdat on Instagram – https://www.instagram.com/mo_gawdat/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: - Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. - fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Timestamps: • 00:00 The Ethical Dilemma of AI in Warfare • 00:31 Introduction to Part Two with Mo Gawdat • 00:58 AI and Human Happiness: A Complex Relationship • 03:18 The Power and Responsibility of Technology • 05:08 The Rise of AI and Its Impact on Society • 08:31 The Future of AI: Abundance or Destruction? • 19:53 The Role of Ethics in AI Development • 22:39 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Can Happiness Really Be Engineered? Mo Gawdat Says Yes—And Here’s How. I know what you’re thinking… ANOTHER episode on happiness? Haven’t we heard it all before? This one’s different. The code is cracked, and you’re about to learn exactly how it works. Joining us today is Mo Gawdat, bestselling author of Unstressable and former Chief Business Officer of Google X. Mo sits down with Dave to deliver a practical, science-backed approach to hacking your mind and body for lasting joy. Mo dives into the raw science behind happiness and stress—revealing how your brain runs on algorithms that you can actually reprogram. Discover why dopamine might be sabotaging your joy, how to decode the four types of stress, and biohacks that can flip the script on your mental and physical resilience. He also shares the deeply personal story of how he turned unimaginable tragedy into a global mission for happiness and purpose. Mo’s insights will challenge everything you thought you knew about living a fulfilled life. What You’ll Learn: • The happiness algorithm—and how to make it work for you • Why dopamine addiction is robbing you of joy (and how to fix it) • The four stress modalities and how to regain control • Biohacks that build resilience—like cold plunges, gratitude, and micro-habits • How small mindset shifts can create major life transformations And don’t miss Part 2, dropping in two days! Dave and Mo explore the intersection of happiness and AI, revealing how to get them both working FOR you instead of against you. Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Mo Gawdat’s Book: Scary Smart – https://a.co/d/6DukqyW Mo Gawdat’s Book: Unstressable – https://a.co/d/hrbpY9O Follow Mo Gawdat on Instagram – https://www.instagram.com/mo_gawdat/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: Neurohacker | Go to https://qualialife.com/dave and use code Dave for 15% off. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Timestamps: 00:00 – Intro 00:31 – Introduction to The Human Upgrade 00:45 – Dave Asprey’s AI Background 01:13 – Introducing Mo Gawdat and His Work 01:51 – From Scary Smart to Unstressable 02:40 – The Journey to Happiness 13:10 – Understanding Stress and Its Mechanisms 17:26 – The Four Modalities of Stress 24:16 – Mental Stress and the Happiness Flowchart 31:34 – Sources of Stress: Trauma, Obsessions, Noise, and Nuisances 33:27 – Understanding Modern PTSD 34:09 – The Role of Obsessions and Noise 36:24 – Biohacking for Resilience 37:58 – The Power of Gratitude 40:12 – The Happiness Equation 54:37 – Dopamine vs. Serotonin 01:03:00 – The Benefits of Cold Therapy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.