This Could Prevent Type 1 Diabetes - SAB-142 Explained
Can we stop type 1 diabetes before it starts? I’m joined by Sam Reich, CEO of SAB Bio, and Dr. Mike Haller, a leading T1D researcher, to explore an innovative new therapy called SAB-142. Unlike traditional thymoglobulin, which is derived from rabbits, SAB’s therapy uses a fully human version produced by genetically engineered cows—potentially eliminating harmful side effects like serum sickness. We unpack how this treatment could delay or prevent the onset of type 1 diabetes and how it builds on research behind Teplizumab. Plus, we talk about the pivotal role NIH funding plays in advancing diabetes innovation. If you're curious about the future of diabetes prevention, you won’t want to miss this.
Learn about Omnipod 5 (today's sponsor)*
T1D Exchange Registry Sign up (US residents only)
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DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care.
*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.
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1:11:30
Getting Started on AAPS - The Open Source AID for Android
We explore Android APS (AAPS)—a powerful open-source automated insulin delivery system that runs on Android phones and uses the advanced o-ref algorithm. AAPS offers features like Dynamic ISF (Insulin Sensitivity Factor), Dynamic CR (Carb Ratio), Unannounced Meal detection (UAM), and Super Micro Boluses (SMBs), making it one of the most customizable diabetes tech options out there. Our guest, Austin Sympson, a competitive cyclist with type 1 diabetes, shares his experience after three months on AAPS and what it's like getting started. We dive into why he switched from commercial systems, the setup process, and how he uses Temp Targets and his Garmin smartwatch to stay in range.
Learn about Omnipod 5 (today's sponsor)*
T1D Exchange Registry Sign up (US residents only)
Watch This Episode On Youtube
Join our Newsletter | Support us on Patreon
Follow Diabetech: Instagram | Tik Tok | YouTube | Facebook
DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care.
*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.
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1:06:58
The Twiist Pump is Coming - What You Need to Know
The twiist insulin pump from Sequel Med Tech is releasing in Q2 of 2025. is bringing a new spin to tubed pump therapy. I met with Sequel's CEO to dive into twiist's launch CGM integration with Libre 3 Plus to its advanced occlusion technology designed for more reliable insulin delivery. We also break down how patients will access twiist through pharmacy benefit managers, a shift that could make the pump more accessible. For more coverage on the biggest diabetes tech announcements at ATTD, check out my social (@diabe_tech) and our recent podcast episode covering the biggest news!
Learn about Omnipod 5 (today's sponsor)*
T1D Exchange Registry Sign up (US residents only)
Watch This Episode On Youtube
Watch Next: twiist First Look | twiist Explained
Join our Newsletter | Support us on Patreon
Follow Diabetech: Instagram | Tik Tok | YouTube | Facebook
DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care.
*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.
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18:01
ATTD 2025: The Biggest Diabetes Tech Announcements
Endocrinologist David Ahn and I break down the biggest diabetes tech announcements from the ATTD conference in Amsterdam! We dive into the highly anticipated Twiist pump, the newly unveiled and more powerful Kaleido 2, Tandem’s game-changing Control IQ+ algorithm update, Dexcom’s 15-day sensor, and more. This was a HUGE week for diabetes innovation—What are you most excited for? Let us know on Youtube!
Watch This Episode On Youtube
Learn about Omnipod 5 (today's sponsor)*
T1D Exchange Registry Sign up (US residents only)
Join our Newsletter | Support us on Patreon
Follow Diabetech: Instagram | Tik Tok | YouTube | Facebook
Follow David's Channels: Tik Tok | Instagram
DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care.
*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.
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30:56
How the ADA Sets its Standards of Care for Diabetes
The ADA’s Standards of Care shape diabetes treatment, technology access, and insurance coverage worldwide. In this episode, we break down the latest updates, including a major new recommendation that all people with type 2 diabetes—regardless of insulin use—have access to CGM. We also explore the ADA’s stance on emerging diabetes technologies and why these guidelines are considered the “gold standard” for diabetes management. Joining me is Dr. Grazia Aleppo, a leading endocrinologist and former Chair of the ADA’s Diabetes Technology Section, who shares insights into how these recommendations are developed and their impact on diabetes care.
Watch This Episode On Youtube
Learn about Omnipod 5 (today's sponsor)*
T1D Exchange Registry Sign up (US only)
Support Diabetech on Patreon | Diabetech Community Discord
Follow me here: Instagram | Tik Tok | YouTube | Facebook
DISCLAIMERS: This podcast is not medical advice. Always consult with your doctor before making changes to your health care.
*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.
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