#175 A Revolution in HIV Prevention & The PURPOSE Trials: Beyond Journal Club Segment with NEJM Group
How good are we at preventing HIV? How do efficacy and effectiveness differ? We journey from oral pre-exposure prophylaxis (PrEP) to long-acting injectables, and then to the PURPOSE trials, which look at the use of long-acting lenacapavir as PrEP — a potential game-changer in the field of HIV.Listen to this latest episode of Beyond Journal Club, a collaboration between CoreIM and NEJM Group, where we put research into context, telling the story of how we arrived at the current standard of care, appreciating the clinical question of the trial at hand, and interpreting what the findings may mean for these patients.🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply!🔹 Transcript and Show NotesTimestamps:(02:25) | HIV PrEP Daily Truvada and Descovy (07:48) | On-Demand Prep(13:25) | Purpose Trials(20:56) | Discussion of Effectiveness to Efficacy Tags: CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, HIV Prevention, Infectious Disease Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Thrive Market for 30% off your first order, plus a FREE $60 gift! : https://thrivemarket.com/coreim* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
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#174 Lp(a) and ASCVD Risk: 5 Pearls Segment
What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a). Learn how to interpret results, counsel patients, and navigate topics with limited data like aspirin and PCSK9 inhibitors in treatment.🔹 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! Use the code CORE50 to get 50% off your first month with Freed🔹 Transcript and Show NotesTimestamps:(02:17) | Pearl 1: What makes Lp(a) unique? How does it raise ASCVD risk?(10:32) | Pearl 2: Who should be tested for Lp(a)? When and why?(16:54) | Pearl 3: Understanding and interpreting Lp(a) levels(24:04) | Pearl 4: How does an elevated Lp(a) affect management?(37:05)| Pearl 5: The role of aspirin and PCSK9 inhibitors in Lp(a)Tags: CoreIM, Internal Medicine, Primary Care, Preventive Cardiology, Atherosclerosis, Lipid Management, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical StudentFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Thrive Market for 30% off your first order, plus a FREE $60 gift! : https://thrivemarket.com/coreim* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
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#173 Hypercoagulability Workup: 5 Pearls Segment
A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the nuances and practical approaches!🔹 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! Use the code CORE50 to get 50% off your first month with Freed🔹 This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a special discount at factor75.com.Transcript and Show NotesTimestamps:(02:07) | Pearl 1: Reframing Provoked vs. Unprovoked to Reversibility(09:12) | Pearl 2: How can Virchow's Triad help us categorize the etiology of a clot?(17:01) | Pearl 3: What factors affect anti-thrombin III, Protein C and Protein S deficiency(28:50) | Pearl 4: Is the Factor V Leiden or Prothrombin Gene Mutation as important as the family history?(38:41) | Pearl 5: Spaced Repetition of Learning PointsTags: CoreIM, Internal Medicine, ClinicalPearls, Medical Education, IMCore, hospitalist, physician assistant, nurse practitioner, medical student, internal medicine, hematologyFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Thrive Market for 30% off your first order, plus a FREE $60 gift! : https://thrivemarket.com/coreim* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
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44:49
#172 Microplastics and Macro CV Health Problems: Beyond Journal Club on APACHe Study with NEJM Group
What is the impact of microplastics on human health? How can we use observational data to support the argument that microplastics may lead to poor health outcomes?Join us as we tackle these questions and discuss the APAChE study on microplastics and cardiovascular disease on this episode of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group.🔹 Transcript and Show Notes🔹 Behind The Scenes YouTube VideoThis episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a special discount at factor75.com.Timestamps:(02:24) | Introduction to Plastic's Key Players(07:59) | Bradhill/Observational Work(10:33) | APAChE Study Deep Dive(18:03) | Discussion📢 Special Thanks:🎙️ Audio Editing: Jerome Reyes📊 Graphics: Dr. Jimin HwangTags:CoreIM, Environmental Health, Medical Education, IMCore, Public Health, Clinical Pearls, Physician, Medical Student, Nurse Practitioner, EpidemiologyFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Thrive Market for 30% off your first order, plus a FREE $60 gift! : https://thrivemarket.com/coreim* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
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33:36
#171 Hospice Music Therapy: Bonus Episode
What is the last sense to go? How can music create connection, ease anxiety, and help process emotions at the end of life? Join Dr. Jafar Al-Mondhiry, Dr. Harry Han, and music therapist Bryanna Tobin as they explore the power of music therapy in hospice care, sharing moving stories and clinical insights.🔹 This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a special discount at factor75.com.🔹 Transcript and Show NotesTimestamps:(00: 39) | 1st: What is Music Therapy in Hospice?(07:59) | 2nd: A Powerful Story(14:19) | 3rd: Challenges in the Field of Music TherapyTags: IMCore, CoreIM, primary care, palliative care, end-of-life, oncology nurse practitioner, pharmacist, physician assistantFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Thrive Market for 30% off your first order, plus a FREE $60 gift! : https://thrivemarket.com/coreim* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges
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