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Science History Podcast

Podcast Science History Podcast
Frank A. von Hippel
Monthly interviews on important moments in the history of science.

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5 z 88
  • Episode 88. Polymerase Chain Reaction: Henry Erlich
    The history of science is punctuated by moments of technological innovation that produce a paradigm shift and a subsequent flurry of discovery. A recent technological innovation that generated diverse discoveries, ranging from a profound shift in our understanding of the origin of humanity to a seismic change in the criminal justice system, is the polymerase chain reaction, or PCR. With us to discuss the history of PCR is one of its innovators, Henry Erlich. As Director of the Human Genetics Department at Cetus Corporation and later as Director of Human Genetics and Vice President of Exploratory Research at Roche Molecular Systems, Henry led developments in diagnostic applications for infectious and autoimmune diseases, forensic genetics, and organ transplantation. His laboratory performed the first forensic DNA case in the United States in 1986 and the first DNA-based post-conviction exoneration. Henry has published over 450 journal articles and three books, which include PCR Technology: Principles and Applications for DNA Amplification, Silent Witness: Forensic DNA Analysis in Criminal Investigations and Humanitarian Disasters, and Genetic Reconstruction of the Past: DNA Analysis in Forensics and Human Evolution. Henry has received numerous awards, including the Association for Molecular Pathology Award for Excellence (2000) and the Profiles in DNA Courage Award (National Institute of Justice, 2005).
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  • Episode 87. Meitner's Atom: Marissa Moss
    Lise Meitner was the most important female physicist of the 20th century. She made fundamental discoveries on the atom, including, most famously, being the first to discover the idea of fission. This she did as she puzzled over experimental results generated by her colleague Otto Hahn. Hahn, but not Meitner, received the Nobel Prize in Chemistry for this monumental discovery. More generally, Meitner overcame profound obstacles facing women in science to become a central figure in physics during its heyday as she worked with the likes of Niels Bohr and Albert Einstein to understand the atom, and hence the universe. With us to discuss the life and legacy of Lise Meitner is Marissa Moss. Marissa is the award-winning author and illustrator of over 70 books for children and young adults, including the book we discuss today, The Woman Who Split the Atom: The Life of Lise Meitner.
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  • Episode 86. Quantum Mechanics: Jim Baggott
    Humanity's understanding of the universe radically altered with the advent of quantum mechanics in the early 20th century. The theory of quantum mechanics describes how nature behaves at or below the scale of atoms, and the road to that theory was littered with seemingly insurmountable obstacles. With us to discuss the development of quantum mechanics, and the major schools of thought represented by Neils Bohr and Albert Einstein, is Jim Baggott. Today we discuss many of the key players in the development of quantum mechanics, including Bohr, Einstein, Wolfgang Pauli, Werner Heisenberg, Erwin Schrödinger, Max Planck, and Max Born.
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    2:15:56
  • Episode 85. SWOPSI: Joel Primack & Robert Jaffe
    Societal problems big and small typically have a scientific element, often in a central way, yet most scientists are not directly involved in policy. My guests sought to change that in 1969 when they created the Stanford Workshops on Social and Political Issues, or SWOPSI. SWOPSI was founded by three students, two of whom are with us today: Joel Primack and Robert Jaffe. The third student was Joyce Kobayashi. Also with us today is my uncle Frank, who worked on some of the early SWOPSI initiatives. In this episode, I ask Joel, Bob and Frank: How did they hack Stanford's rules for course credit to create workshops run by graduate students? What were the goals of SWOPSI? How effective were the workshops in tackling local vs. national or international problems? How did SWOPSI help to create programs for scientists to advise Congress on technical issues? Why did SWOPSI perish as an institution at Stanford? How has US military-sponsored research evolved since the Second World War? And is SWOPSI a good model for young scientists today who want to solve societal problems?
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    1:43:49
  • Episode 84. The Academy: Bret Stephens
    Institutions of higher education, especially in the United States, have received a great deal of attention over the past two generations regarding their ideological march to the left, and the impacts, real or imagined, on society at large. Criticism of American universities has sharpened since Oct. 7, 2023, as the Hamas attack on Israel was closely followed by campus protests against Israel. The ensuing turmoil resulted in the temporary closure of campuses, the resignations of college presidents, the cancellations of speakers and commencement ceremonies, and congressional investigations. How did American universities get to this moment? What are the implications for free speech, social cohesion, and democracy? And what are the repercussions for scholarship and science? My guest, Bret Stephens, has written extensively on the state of American universities, illiberalism, and antisemitism. Bret worked as an assistant editor at Commentary magazine from 1995-1996, after which he moved to the Wall Street Journal. From 2002-2004, Bret served as the editor-in-chief of The Jerusalem Post, where he oversaw the most comprehensive overhaul of the paper's content in its 70-year history. He then returned to the Wall Street Journal, where he won the 2013 Pulitzer Prize for Commentary. Bret moved to The New York Times in 2017, where he writes as an opinion columnist. He is also a contributor to NBC News and MSNBC, a contributing editor for Commentary magazine, and the editor-in-chief of SAPIR: A Journal of Jewish Conversations.
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