Science Friday

• A Vaccine For Pancreatic Cancer Continues To Show Promise

  Pancreatic cancer is notoriously difficult to treat, and about 90% of diagnosed patients die from the disease. A team at Memorial Sloan Kettering has been working to improve those outcomes by developing a new mRNA vaccine for pancreatic cancer.A few years ago, the team embarked on a small trial to test the vaccine’s safety. Sixteen patients with pancreatic cancer received it, and even though it was a small study, the results were promising: Half the participants had an immune response, and in those patients the cancer hadn’t relapsed after 18 months.This week, the team released a new study in Nature following those same patients, and found six out of eight who responded to the vaccine in the first study did not have their cancer return more than three years later.Joining host Flora Lichtman to talk about these results, and what they could mean for the future of cancer treatment, is study author and surgeon Dr. Vinod Balachandran, director of The Olayan Center for Cancer Vaccines at Memorial Sloan Kettering, based in New York City.Transcripts for each segment will be available after the show airs on sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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• Why Are Flu And Other Viral Infection Rates So High This Year?

  It’s been an unusually tough winter virus season. Rates of flu-like infections are higher than they’ve been in nearly 30 years. And for the first winter since the start of the COVID-19 pandemic, flu deaths have surpassed COVID deaths. Add to that a higher-than-average year for norovirus, a nasty type of stomach bug.Then there’s the emerging threat of avian flu. While there is no evidence of human-to-human transmission of the virus, about 70 people in the US have contracted the virus from livestock since April 2024.To make sense of the latest viral trends, Host Flora Lichtman talks with Dr. Katelyn Jetelina, epidemiologist and author of the newsletter “Your Local Epidemiologist”; and Dr. Erica Shenoy, chief of infection control at Mass General Brigham hospital.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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• Making Sense Of Federal Cuts To Science—And What Comes Next

  Last week, some 3,500 people from across scientific fields gathered in Boston for the annual meeting of the American Association for the Advancement of Science (AAAS). The organization’s CEO, Dr. Sudip Parikh, gave a rousing speech to attendees.“Destruction for the ill-conceived notion of cutting costs didn’t put an American on the moon, and it didn’t wipe smallpox from the face of the Earth,” Parikh said in opening remarks.He was referring, of course, to the huge funding cuts and mass firings happening across federal science and health agencies under the Trump administration. Over the last few weeks, news of these cuts has been frequent—along with the cancellation of grants that include certain prohibited words and the disappearance of data from agency websites.So what’s happening, and how should the scientific community respond? Host Flora Lichtman sat down with Dr. Sudip Parikh to discuss the importance of this point in time for American science and technology, what cuts for “efficiency” are getting wrong, and what’s at stake in the next few weeks.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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• Tomb Of Egyptian King Unearthed | Why The Internet Was Captivated By A Hideous Fish

  Finding the original tomb of the royal is one of the most significant developments in Egyptian archeology in recent history. Also, a video of a gloriously creepy anglerfish inspired tears and poetry online. But why was this deep-sea dweller near the surface at all?Royal Tomb Of Egyptian King Thutmose II UnearthedA British-Egyptian team has made one of the most significant Egyptian archeological finds in recent history: the tomb of pharaoh King Thutmose II, who ruled sometime between 2000 and 1001 BCE. This is the first tomb of a pharaoh unearthed since Tutankhamun’s in 1922.Thutmose II’s mummified remains were found two centuries ago, but they had been moved from his original tomb, the location of which remained a mystery until now. Part of the reason why his tomb’s location was such a mystery was that Thutmose II was buried in an area associated with the wives of Egyptian kings, about 1.5 miles west of Egypt’s famous Valley of the Kings.Joining Host Flora Lichtman to talk about this and other science stories of the week is Maggie Koerth, science writer and editorial lead of CarbonPlan, based in Minneapolis, Minnesota.Why The Internet Was Captivated By A Hideous FishLast week, a viral video likely floated to the top of your feed: a rare black seadevil anglerfish, which looks like a floating head with a frightening amount of teeth and two cloudy eyes, swimming in azure waters. The fish showed up near Spain’s Canary Islands, off the northwestern coast of Africa. It made the news because it was spotted near the surface, while anglerfish normally reside in the deep ocean.So why was she paddling so close to the surface? Was she sick? How unusual is this? And also, why do they even look like that? We had questions.Host Flora Lichtman talks with Dr. Kory Evans, assistant professor of biosciences at Rice University, to separate fact from fish-ction. He also explains new research he helped conduct about the evolutionary history of anglerfish, which could help explain why they look the way they do.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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• What Happens To Your Body When You’re Grieving

  We have lots of expressions to describe the pain of loss—heartache, a broken heart, a punch in the gut. These aren’t just figures of speech: While grief is an emotional experience, it’s also a physical one. Studies show that grief can change your physiology, most dramatically in the cardiovascular and immune systems.One staggering finding? A heart attack is 21 times more likely to happen in the 24 hours after the death of a loved one. And after the death of a parent, risk of ischemic heart disease rises by 41%, and risk of stroke increases by 30%.Dr. Mary-Frances O’Connor has dedicated her career to understanding the physiology behind grief and grieving. She joins Host Flora Lichtman to discuss what she’s learned over the years, and her new book The Grieving Body.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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